Nine papers
by Thomas G Osimitz
- RJ Price, MP Scott, C Cantrill, LG Higgins, M Moreau, M Yoon, HJ Clewell, MR Creek, TG Osimitz, JB Houston, and BG Lake. Kinetics of metabolism of deltamethrin and cis- and trans-permethrin in vitro. Studies using rat and human liver microsomes, isolated rat hepatocytes and rat liver cytosol. Xenobiotica 51 (1) : 40-50 (Jan 26, 2021). [abstract] [pubmed]
- L Hedges, S Brown, AK MacLeod, M Moreau, M Yoon, MR Creek, TG Osimitz, and BG Lake. Metabolism of bifenthrin, β-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes. Xenobiotica 50 (12) : 1434-1442 (Dec 22, 2020). [abstract] [pubmed]
- LG Higgins, LR Chatham, SL Tomczynski, AK MacLeod, M Moreau, HJ Clewell, M Yoon, MR Creek, TG Osimitz, and BG Lake. Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats. Toxicology 443 : 152563 (Oct 14, 2020). [abstract] [pubmed]
- P Mallick, G Song, AY Efremenko, SN Pendse, MR Creek, TG Osimitz, RN Hines, P Hinderliter, HJ Clewell, BG Lake, M Yoon, and M Moreau. Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids. Toxicol Sci 176 (2) : 460-469 (Aug 1, 2020). [abstract] [pubmed]
- P Mallick, M Moreau, G Song, AY Efremenko, SN Pendse, MR Creek, TG Osimitz, RN Hines, P Hinderliter, HJ Clewell, BG Lake, and M Yoon. Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans. Toxicol Sci 173 (1) : 86-99 (Jan 1, 2020). [abstract] [pubmed]
- G Song, M Moreau, BG Lake, H Wu, JV Bruckner, CA White, TG Osimitz, MR Creek, PM Hinderliter, HJ Clewell, M Yoon, and AY Efremenko. Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation. Toxicol Sci 169 (2) : 365-379 (Jun 1, 2019). [abstract] [pubmed]
- L Hedges, S Brown, AK MacLeod, A Vardy, E Doyle, G Song, M Moreau, M Yoon, TG Osimitz, and BG Lake. Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes. Xenobiotica 49 (5) : 521-527 (May 4, 2019). [abstract] [pubmed]
- L Hedges, S Brown, A Vardy, E Doyle, M Yoon, TG Osimitz, and BG Lake. Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations. Xenobiotica 49 (4) : 388-396 (Apr 19, 2019). [abstract] [pubmed]
- G Song, X Sun, RN Hines, DG McCarver, BG Lake, TG Osimitz, MR Creek, HJ Clewell, and M Yoon. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. Drug Metab Dispos 45 (5) : 468-475 (May 22, 2017). [abstract] [pubmed]