Five papers
by James S Bus
- ME Andersen, G Cruzan, MB Black, SN Pendse, DE Dodd, JS Bus, SS Sarang, MI Banton, R Waites, DB Layko, and PD McMullen. Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment. Regul Toxicol Pharmacol 96 : 153-166 (Jul 17, 2018). [abstract] [pubmed]
- G Cruzan, JS Bus, ME Andersen, GP Carlson, MI Banton, SS Sarang, and R Waites. Based on an analysis of mode of action, styrene-induced mouse lung tumors are not a human cancer concern. Regul Toxicol Pharmacol 95 : 17-28 (Jun 26, 2018). [abstract] [pubmed]
- ME Andersen, G Cruzan, MB Black, SN Pendse, D Dodd, JS Bus, SS Sarang, MI Banton, R Waites, and PD McMullen. Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures. Toxicol Appl Pharmacol 335 : 28-40 (Nov 15, 2017). [abstract] [pubmed]
- G Cruzan, JS Bus, MI Banton, SS Sarang, R Waites, DB Layko, J Raymond, D Dodd, and ME Andersen. Editor's Highlight: Complete Attenuation of Mouse Lung Cell Proliferation and Tumorigenicity in CYP2F2 Knockout and CYP2F1 Humanized Mice Exposed to Inhaled Styrene for up to 2 Years Supports a Lack of Human Relevance. Toxicol Sci 159 (2) : 413-421 (Oct 1, 2017). [abstract] [pubmed]
- ME Andersen, MB Black, JL Campbell, SN Pendse, HJ Clewell, LH Pottenger, JS Bus, DE Dodd, DC Kemp, and PD McMullen. Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver. Toxicol Appl Pharmacol 332 : 149-158 (Oct 1, 2017). [abstract] [pubmed]