One paper
by ScitoVation authors
-
K Mansouri,
N Kleinstreuer,
AM Abdelaziz,
D Alberga,
VM Alves,
PL Andersson,
CH Andrade,
F Bai,
I Balabin,
D Ballabio,
E Benfenati,
B Bhhatarai,
S Boyer,
J Chen,
V Consonni,
S Farag,
D Fourches,
AT García-Sosa,
P Gramatica,
F Grisoni,
CM Grulke,
H Hong,
D Horvath,
X Hu,
R Huang,
N Jeliazkova,
J Li,
X Li,
H Liu,
S Manganelli,
GF Mangiatordi,
U Maran,
G Marcou,
T Martin,
E Muratov,
DT Nguyen,
O Nicolotti,
NG Nikolov,
U Norinder,
E Papa,
M Petitjean,
G Piir,
P Pogodin,
V Poroikov,
X Qiao,
AM Richard,
A Roncaglioni,
P Ruiz,
C Rupakheti,
S Sakkiah,
A Sangion,
KW Schramm,
C Selvaraj,
I Shah,
S Sild,
L Sun,
O Taboureau,
Y Tang,
IV Tetko,
R Todeschini,
W Tong,
D Trisciuzzi,
A Tropsha,
G Van Den Driessche,
A Varnek,
Z Wang,
EB Wedebye,
AJ Williams,
H Xie,
AV Zakharov,
Z Zheng,
and
RS Judson.
CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity.
Environ Health Perspect
128
(2)
: 27002
(Feb 7, 2020).
[abstract]
[pubmed]
Endocrine disrupting chemicals (EDCs) are xenobiotics that mimic the interaction of natural hormones and alter synthesis, transport, or metabolic pathways. The prospect of EDCs causing adverse health effects in humans and wildlife has led to the development of scientific and regulatory approaches for evaluating bioactivity. This need is being addressed using high-throughput screening (HTS) in vitro approaches and computational modeling.