One paper
by ScitoVation authors
-
WM Casey,
X Chang,
DG Allen,
PC Ceger,
NY Choksi,
JH Hsieh,
BA Wetmore,
SS Ferguson,
MJ DeVito,
CS Sprankle,
and
NC Kleinstreuer.
Evaluation and Optimization of Pharmacokinetic Models for in Vitro to in Vivo Extrapolation of Estrogenic Activity for Environmental Chemicals.
Environ Health Perspect
126
(9)
: 97001
(Sep 1, 2018).
[abstract]
[pubmed]
To effectively incorporate in vitro data into regulatory use, confidence must be established in the quantitative extrapolation of in vitro activity to relevant end points in animals or humans.