One paper
by ScitoVation authors
-
JC van Eijkeren,
JD Olie,
SM Bradberry,
JA Vale,
I de Vries,
HJ Clewell,
J Meulenbelt,
and
CC Hunault.
Modeling the effect of succimer (DMSA; dimercaptosuccinic acid) chelation therapy in patients poisoned by lead.
Clin Toxicol (Phila)
55
(2)
: 133-141
(Feb 5, 2017).
[abstract]
[pubmed]
Kinetic models could assist clinicians potentially in managing cases of lead poisoning. Several models exist that can simulate lead kinetics but none of them can predict the effect of chelation in lead poisoning. Our aim was to devise a model to predict the effect of succimer (dimercaptosuccinic acid; DMSA) chelation therapy on blood lead concentrations.